BlueRock Therapeutics, a clinical stage biopharmaceutical company and wholly-owned subsidiary of Bayer AG, announced today the dose administration for the first patient in Canada in partnership with the University Health Network in a Phase 1 (Ph1), open-label trial of pluripotent stem cell-derived dopaminergic neurons in patients with advanced Parkinson’s disease. The purpose of the Ph1 clinical trial is to evaluate the safety, tolerability and preliminary efficacy of DA01 in patients with Parkinson’s disease.
“It is incredibly exciting to be a part of delivering this first-of-its-kind authentic cellular medicine to patients in Canada, with the hope of regenerating lost function and possibly improving and reversing Parkinson’s disease,” said Joachim Fruebis, Ph.D., Chief Development Officer of BlueRock.
Dr. Andres Lozano, O.C., M.D., Ph.D., F.R.C.S.C., F.R.S.C., F.C.A.H.S., Principal Investigator at the Krembil Brain Institute, University Health Network states, “with this surgery, our objective is to use authentic cells, to have them integrate into the brain and restore lost physiologic function. If successful, this treatment could have implications for the Parkinson’s community both in Canada and beyond.”